NCT03741153

Association Between Pseudoexfoliation Syndrome and Diabetes Mellitus

The Possible Association Between Pseudoexfoliation Syndrome and Diabetes Mellitus in an Egyptian Population

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

Pseudoexfoliation syndrome (PEX) is characterized by the deposition of a distinctive fibrillar material in the anterior segment of the eye and was first described in 1917 by Lindberg. It is frequently associated with open angle glaucoma, known as pseudoexfoliation glaucoma, which is one of the most common identifiable forms of secondary open angle glaucoma worldwide. Despite extensive research, the exactchemical nature of the fibrillar material is unknown. It is believed to be secreted multifocally in the iris pigment epithelium, the ciliary epithelium, and the peripheral anterior lens epithelium.

Conditions

• Lens Diseases

Interventions

Type	Name	Description
DEVICE	slit lamp	1. Presence of white grayish exfoliation material on the anterior lens capsule and / or the pupillary margin. 2. Poor pupillary dilatation due to atrophy of the dilator pupillae muscle. 3. The presence of pseudoexfoliative material (PXF)in cilliary processes and zonules. 4. presence of PXF material scattered on corneal endothelium. 5. Flecks of the exfoliative material on the anterior chamber which leads to glaucoma.

Timeline

• Start date: 2019-01-01
• Primary completion: 2020-12-01
• Completion: 2021-03-14
• First posted: 2018-11-14
• Last updated: 2018-11-14