Clinical Trials Directory

Trials / Active Not Recruiting

Active Not RecruitingNCT03740542

Pyloroplasty Versus No Pyloroplasty in Patients Undergoing Esophagectomy

A Phase III Randomized Trial of Pyloroplasty Versus No Pyloroplasty in Patients Undergoing Esophagectomy

Status
Active Not Recruiting
Phase
N/A
Study type
Interventional
Enrollment
143 (actual)
Sponsor
University of Pittsburgh · Academic / Other
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Not accepted

Summary

This research study is a phase III randomized trial to study the value of the addition of a pyloroplasty procedure versus no pyloroplasty procedure during the performance of esophagectomy. Pyloroplasty is a type of pyloric drainage procedure.

Detailed description

Patients selected for enrollment in this study will be adults (18-85 years of age) that have been scheduled for exploration, and possible esophagectomy. Prior to surgery, patients will be randomized to one of two groups. Group A will have a pyloroplasty performed as part of the esophagectomy procedure. Group B will not have a pyloroplasty performed. Postoperative patient outcomes will be assessed for 24 months.

Conditions

Interventions

TypeNameDescription
PROCEDUREEsophagectomySurgical removal of part of esophagus
PROCEDUREPyloroplastypyloric drainage procedure

Timeline

Start date
2018-11-27
Primary completion
2023-02-14
Completion
2027-03-01
First posted
2018-11-14
Last updated
2026-04-14

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT03740542. Inclusion in this directory is not an endorsement.