NCT03738969

Longitudinal Study of Different Surgical Approaches in Chinese Patients of Uterine Cervical Cancer

Longitudinal Study of Different Surgical Approaches in Chinese Patients of Cervical Cancer

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 3,000 (estimated)
• Sponsor: Lei Li · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

This multi-center longitudinal study aims to compare the survival outcomes (including overall survival, progression-free survival and disease-free survival between uterine cervical patients receiving different surgical routes (vaginal, laparotomy and laparoscopy), which is the primary study objective. All clinical and pathological data would be retracted from case reviews, and all survival data would be reached by clinic, telephone and mail follow-up. This study also would analyze the impact on survival outcomes of other factors, including nerve-sparing techniques, neoadjuvant chemotherapy, neoadjuvant radiotherapy and infection of human papillomavirus. The predictive effects of different following protocol and imaging plans will be also compared. Last, the influences of surgical routes on the fertility outcomes (pregnancy and its complications) and the ovarian reserve are important secondary study objectives.

Conditions

• Uterine Cervical Neoplasms
• Laparotomy
• Laparoscopy
• Survival
• Mortality
• Recurrence

Interventions

Type	Name	Description
PROCEDURE	Laparotomic radical hysterectomy	Radical hysterectomy applied by laparotomy
PROCEDURE	Laparoscopic radical hysterectomy	Radical hysterectomy applied by laparoscopic

Timeline

• Start date: 2018-11-10
• Primary completion: 2022-12-23
• Completion: 2023-12-23
• First posted: 2018-11-13
• Last updated: 2018-11-14

Locations

1 site across 1 country: China