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Active Not RecruitingNCT03738553

Multiparametric MRI for Assessing Breast Cancer Response to Anti-HER2 Therapy

Status
Active Not Recruiting
Phase
Study type
Observational
Enrollment
13 (actual)
Sponsor
University of Washington · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is a single institution, observational research study in which patients are observed using DWI/DCE MRI imaging before and after receiving neoadjuvant anti-HER2 therapy.

Detailed description

This is not a treatment trial. Patients will be treated according to the plan developed by their medical oncologists. Only patients planning to receive anti-HER2 therapy as part of planned systemic therapy will be eligible for this imaging study. Patients and their referring oncologist will be asked to start the anti-HER2 therapy 2-3 weeks prior to surgery and after the pre-therapy MRI.

Conditions

Interventions

TypeNameDescription
DEVICEMRIDiffusion Weighted Imaging and Dynamic Contrast enhanced MRI
DRUGTrastuzumabSingle dose of Trastuzumab prior to surgery

Timeline

Start date
2013-08-01
Primary completion
2020-09-01
Completion
2026-03-01
First posted
2018-11-13
Last updated
2025-10-29

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03738553. Inclusion in this directory is not an endorsement.

Multiparametric MRI for Assessing Breast Cancer Response to Anti-HER2 Therapy (NCT03738553) · Clinical Trials Directory