NCT03738514

Comparison of Efficacy of 5% Fluorocalcium Phosphosilicate Dentifrice and Potassium Nitrate Dentifrice on Dentinal Hypersensitivity

Comparison Of Efficacy Of Dentifrice Containing 5% Fluorocalcium Phosphosilicate With Dentifrice Containing Potassium Nitrate And Placebo On Dentinal Hypersensitivity: A Triple Masked Randomized Controlled Clinical Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 120 (actual)
• Sponsor: Government Dental College and Research Institute, Bangalore · Academic / Other
• Sex: All
• Age: 25 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Aim of this study was to assess and compare the efficacy of a dentifrice containing 5% fluoro calcium phosphosilicate and dentifrice containing potassium nitrate on Dentinal Hypersensitivity (DH) compared to a placebo over a period of 6 weeks.

Detailed description

A total of 120 subjects were divided into 3 groups randomly. Group 1 was given the dentifrice containing 5% fluoro calcium phosphosilicate ,Group 2 was given the dentifrice containing potassium nitrate and group 3 was given placebo. Sensitivity scores (VAS score) were recorded at baseline, 2 weeks, 6 weeks.

Conditions

• Dentinal Hypersensitivity

Interventions

Type	Name	Description
OTHER	5% fluorocalcium phosphosilicate dentifrice	dentifrice containing 5% fluorocalcium phosphosilicate and VAS score assessed at Baseline, 2 weeks, 6 weeks
OTHER	5% potassium nitrate dentifrice	5% potassium nitrate dentifrice and VAS score assessed at Baseline, 2weeks, 6 weeks.
OTHER	Placebo dentrifice	placebo dentifrice and VAS score assessed at Baseline, 2weeks, 6 weeks

Timeline

• Start date: 2017-12-22
• Primary completion: 2018-02-09
• Completion: 2018-02-22
• First posted: 2018-11-13
• Last updated: 2018-11-13

Locations

1 site across 1 country: India