NCT03738280

Non-hypovascular Solid Pancreatic Lesions: Role of EUS

Role of EUS in Differential Diagnosis and Malignancy Prediction of Non-hypovascular Solid Pancreatic Lesions: A Prospective Observational Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 154 (actual)
• Sponsor: Azienda Ospedaliera Universitaria Integrata Verona · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Vascular pattern of solid pancreatic lesions (SPLs) has been investigated by different abdominal imaging modalities and by contrast-enhanced endoscopic ultrasonography (CE-EUS). Compared with surrounding pancreatic parenchyma three different patterns have been described: hypo-, iso-, and hypervascular. The majority of SPLs are hypovascular, and the diagnostic relevance of hypoenhanced pattern to predict pancreatic adenocarcinoma (PDAC) is well established. Differently, iso- and hypervascular pattern is not specific and can be expressed by several SPLs, with different clinical behavior and management. To date, poor is know about the role of EUS in differential diagnosis of non-hypovascular SPLs and features associated with malignancy.

Conditions

• Solid Pancreatic Neoplasms
• Endoscopic Ultrasound

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Endoscopic ultrasound-fine needle biopsy	Patients with non-hypovascular solid pancreatic lesion undergo endoscopic ultrasound-fine needle biopsy

Timeline

• Start date: 2016-05-01
• Primary completion: 2018-05-01
• Completion: 2019-05-01
• First posted: 2018-11-13
• Last updated: 2019-05-07

Locations

1 site across 1 country: Italy