NCT03737760

"Mind in Motion": Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults

Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 279 (actual)
• Sponsor: University of Florida · Academic / Other
• Sex: All
• Age: 20 Years – 110 Years
• Healthy volunteers: Accepted

Summary

The objective of this study is to determine the central neural control of mobility in older adults by acquiring data with multiple modalities of neuroimaging (EEG, fNIRS, MRI) and associating these data with a comprehensive set of diverse mobility outcomes (clinic-based walking, complex walking and community mobility measures).

Detailed description

This study is a longitudinal, prospective cohort study with a follow-up period of 1.2 - 3.5 years, dependent on when the participant enrolls. Participants will be assessed at baseline, and then every six months for 3.5 years or until the study ends, whichever comes first. The investigators plan to enroll 200 community-dwelling men and women age 70+ years.

Conditions

• Effect of Age-related Changes in the Brain on Walking Ability

Timeline

• Start date: 2019-04-19
• Primary completion: 2025-05-31
• Completion: 2025-05-31
• First posted: 2018-11-09
• Last updated: 2025-07-17

Locations

1 site across 1 country: United States