NCT03736759

Resistance Exercise to Improve Flu Vaccine for Older Adults

Resistance Exercise to Improve Vaccine Outcomes in Older Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 29 (actual)
• Sponsor: University of Houston · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Accepted

Summary

This study evaluates whether resistance exercise will improve immune responses to the seasonal influenza vaccine in older adults. One third of the participants will perform exercise in the arm that receives the vaccine, one third of the participants will perform the same exercise in the arm that does not receive the vaccine, and one third will only receive the vaccine.

Detailed description

Resistance exercise, particularly novel eccentric exercise, recruits immune cells to the targeted muscle. The exercises selected here targets the deltoid and biceps brachii muscles-those same muscles that the flu vaccine is delivered to during typical vaccination.

Conditions

• Influenza, Human

Interventions

Type	Name	Description
BEHAVIORAL	Exercise	10 sets of 5 repetitions of 80% of calculated one-repetition maximum weight of lateral side arm raise and biceps curls, alternating

Timeline

• Start date: 2018-10-08
• Primary completion: 2019-04-30
• Completion: 2021-04-01
• First posted: 2018-11-09
• Last updated: 2022-05-17

Locations

1 site across 1 country: United States