Trials / Unknown
UnknownNCT03735108
Neutrophil Extracellular Traps Mediate Antiphospholipid Antibody-induced Pregnancy Loss
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Shanghai First Maternity and Infant Hospital · Academic / Other
- Sex
- Female
- Age
- 25 Years – 41 Years
- Healthy volunteers
- Accepted
Summary
1. Establish a multi-platform detection system for neutrophil extracellular traps in blood and tissues, and evaluate the detection performance; 2. Comparing the expression levels of neutrophil extracellular traps in peripheral blood and decidua of patients with antiphospholipid antibody-induced pregnancy loss and normal control group; 3. Comparing the expression levels of neutrophil extracellular traps in peripheral blood and decidua of mice with antiphospholipid antibody-induced pregnancy loss and normal control group; 4. After treatment of antiphospholipid antibody-induced mouse abortion model with metformin,the effect of metformin on embryo loss rate and viable embryo body weight was observed.
Conditions
Timeline
- Start date
- 2018-11-01
- Primary completion
- 2019-06-30
- Completion
- 2019-06-30
- First posted
- 2018-11-08
- Last updated
- 2018-11-08
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03735108. Inclusion in this directory is not an endorsement.