NCT03733912

Plasticizers and in Vitro Fertilization Outcomes

To Investigate the Effect of Plasticizers on the Pregnancy in Vitro Fertilization Cycles

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 80 (actual)
• Sponsor: Kaohsiung Veterans General Hospital. · Academic / Other
• Sex: Female
• Age: 30 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

To investigate the effect of Plasticizer metabolites concentration on the in vitro fertilization outcomes

Detailed description

This study was conducted in a medical center in southern Taiwan. 80 infertile female patients, aged 30 to 40 years old with normal ovarian function, receiving IVF treatment in the infertility outpatient were enrolled in this study. The participates were divided into two groups: successful pregnancy in the IVF cycle (n = 40) and non-pregnancy in the IVF cycle (n = 40). After getting the consent of the patients, we plan to do a questionnaire survey. Additionally, environmental dust and urine were sampled and analyzed the concentration of plasticizers metabolites.The aim of this study is to investigate the effect of Plasticizer metabolites concentration on the in vitro fertilization outcomes.

Conditions

• Fertilization in Vitro

Interventions

Type	Name	Description
OTHER	Phthalate metabolites measurement	To measure phthalate metabolites of urine and house dust in Pregnancy and Non-pregnancy groups

Timeline

• Start date: 2018-07-11
• Primary completion: 2020-12-31
• Completion: 2020-12-31
• First posted: 2018-11-07
• Last updated: 2021-02-18

Locations

1 site across 1 country: Taiwan