Trials / Unknown
UnknownNCT03730766
Analysis of the Impact of Helicobacter Pylori on Salivary Microbiome in Adults
Analysis of the Impact of Helicobacter Pylori Infection and Eradication on Salivary Microbiome in Adults by 16S Pyrosequencing
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- Shanghai Jiao Tong University School of Medicine · Academic / Other
- Sex
- All
- Age
- 20 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
Helicobacter pylori (H. pylori), a bacteria transmitted from human to human through upper digestive tract as well as fecal-oral transmission, had infected more than half of people around the world. However, the quantity of H. pylori in oral cavity and its influence on oral microbiota remains to be unclear. The aim of the present study was to examine the effects of H. pylori infection as well as its eradication on oral microbiota.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Esomeprazole | Proton pump inhibitor |
| DRUG | Amoxicillin | Antibiotics for H. pylori eradication |
| DRUG | Bismuth Potassium Citrate | Gastric mucosal protective drug with anti-H. pylori effect |
Timeline
- Start date
- 2018-08-01
- Primary completion
- 2018-11-15
- Completion
- 2018-11-20
- First posted
- 2018-11-05
- Last updated
- 2018-11-05
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03730766. Inclusion in this directory is not an endorsement.