Trials / Unknown
UnknownNCT03729102
Immunological Tolerance After Frequent Rabies Booster Vaccinations
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- Sponsor
- Queen Saovabha Memorial Institute · Academic / Other
- Sex
- All
- Age
- 20 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
To study immunological tolerance effect after frequent rabies booster vaccination
Detailed description
Previous studies had shown lower antibody titers among those who received frequent rabies booster vaccination, compared to ones who had got primary immunization. We study immunological cells i.e., regulatory T cell, regulatory B cell, T follicular helper cell, and cytokines in those who received frequent rabies booster vaccination.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Blood drawn after rabies vaccine booster vaccination | All participants would be given one dose of rabies vaccine and monitor the immunological cells i.e., regulatory T cell, regulatory B cell, T follicular helper cells, cytokines i.e., IL-10, TGF-Beta, and Rabies neutralizing antibody titers, before and after the booster injection |
Timeline
- Start date
- 2020-06-04
- Primary completion
- 2023-12-01
- Completion
- 2023-12-01
- First posted
- 2018-11-02
- Last updated
- 2022-04-29
Locations
1 site across 1 country: Thailand
Source: ClinicalTrials.gov record NCT03729102. Inclusion in this directory is not an endorsement.