Trials / Enrolling By Invitation
Enrolling By InvitationNCT03727399
Identification of Allergen-reactive Antibodies in the Blood of Pollen Allergic Patients
- Status
- Enrolling By Invitation
- Phase
- —
- Study type
- Observational
- Enrollment
- 300 (estimated)
- Sponsor
- Mabylon AG · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The project examines the hypothesis that monoclonal allergen-neutralizing antibodies can be recombinantly produced from B lymphocytes isolated from pollen allergic patients. Patient samples suitable for antibody cloning are selected based on seroprofiling for the respective allergens. The study aims at isolating lymphocytes from patients with potential allergen-neutralizing IgG in serum and to clone antibodies from antibody gene sequences obtained from B cells of those patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | blood withdrawal | Blood withdrawal |
Timeline
- Start date
- 2018-10-01
- Primary completion
- 2025-12-31
- Completion
- 2025-12-31
- First posted
- 2018-11-01
- Last updated
- 2025-05-02
Locations
1 site across 1 country: Switzerland
Source: ClinicalTrials.gov record NCT03727399. Inclusion in this directory is not an endorsement.