NCT03726372

Muscle Relax Affects Outcomes of Robotic Surgery

Effect of Neuromuscular Blockade Protocol on Perioperative Outcomes of Robotic Laparoscopic Surgery

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 192 (estimated)
• Sponsor: Air Force Military Medical University, China · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

During robotic laparoscopic surgery, a high intraperitoneal pressure may result in high airway pressure and inadequate perfusion of the abdominal organs, and as a result the postoperative outcomes. Degree of neuromuscular blockade (NMB) can affect the intraperitoneal pressure. In this study, the patients undergoing robotic laparoscopic surgery will be assigned to deep NMB group and moderate NMB group. Perioperative outcomes including maximal intraperitoneal pressure, maximal intraoptic pressure, quality of emergence, postoperative pain, and incidence of postoperative respiratory complication will be compared. The results of this study will provide evidence for optimizing NMB protocol of robotic laparoscopic surgery.

Conditions

• General Anesthesia
• Postoperative Complications

Interventions

Type	Name	Description
DRUG	Rocuronium	rocuronium is a neuromuscular blocking agent with a duration of 40 minutes
OTHER	continuous infusion	rocuronium is continuously infused
OTHER	intermittent injection	rocuronium is intermittently given

Timeline

• Start date: 2018-11-10
• Primary completion: 2019-11-10
• Completion: 2019-11-10
• First posted: 2018-10-31
• Last updated: 2018-10-31