NCT03726242

Peripheral Nociceptive Effects of Levcromakalim

Study of Local Physiological Effects Following Intradermal and Intramuscular Injection of Levcromacalim

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Danish Headache Center · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Intradermal and intramuscular injection of levcromacalim and placebo (sterile saline) on the forehead and forearm of healthy subjects and the following will be investigated: 1. Prevalence and intensity of pain 2. Prevalence and intensity of itching 3. Occurrence and intensity of local redness and swelling 4. Occurrence and intensity of local changes in skin temperature and blood flow

Conditions

• Pain
• Levcromakalim

Interventions

Type	Name	Description
DRUG	Levcromakalim	To investigate the role of levcromakalim compared with placebo after intradermal and intramuscular injection.
DRUG	Saline	To investigate the role of levcromakalim compared with placebo after intradermal and intramuscular injection.

Timeline

• Start date: 2018-11-01
• Primary completion: 2019-01-20
• Completion: 2019-01-20
• First posted: 2018-10-31
• Last updated: 2019-01-23

Locations

1 site across 1 country: Denmark