Trials / Unknown
UnknownNCT03725254
CRT Versus Surgery for Retroperitoneal or Paraaortic Lymph Node Recurrence of CRC
Curative Chemoradiotherapy Versus Radical Surgery for Retroperitoneal or Paraaortic Lymph Node Recurrence of Colorectal Cancer
- Status
- Unknown
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 180 (estimated)
- Sponsor
- Fudan University · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
The study aims to compare the effects of chemoradiation versus radical surgery in treating retro-peritoneal or para-aortic lymph node metastasis in colorectal cancer. By prolonging patients' progression-free survival, local control rate and overall survival, investigators can conclude the best regimen for colorectal cancer patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | lymphadenectomy | The retroperitoneal lymphadenectomy includes all lymph, fat, and connective tissue in the retroperitoneal space. |
| RADIATION | chemoradiotherapy | Radiation therapy is highly appropriate, based on the characteristics of the lesion and the surrounding critical organs, and select IMRT or stereotactic radiotherapy (SBRT). |
Timeline
- Start date
- 2018-10-20
- Primary completion
- 2021-10-01
- Completion
- 2024-10-01
- First posted
- 2018-10-31
- Last updated
- 2019-01-23
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03725254. Inclusion in this directory is not an endorsement.