Clinical Trials Directory

Trials / Completed

CompletedNCT03725072

Human Absorption, Distribution, Metabolism and Excretion (ADME) of [14C]-Evobrutinib

Phase I, Open Label, Single Dose Study to Determine the Pharmacokinetics, Metabolism, and Excretion of [14C]-Evobrutinib in Healthy Participants

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
6 (actual)
Sponsor
Merck KGaA, Darmstadt, Germany · Industry
Sex
Male
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

The purpose of the study is to determine the absorption, metabolism, and excretion of \[14C\]-evobrutinib in healthy participants

Conditions

Interventions

TypeNameDescription
DRUGEvobrutinibParticipants will receive a single, oral dose of evobrutinib under fasting conditions as a solution, which will contain \[14C\]-evobrutinib.

Timeline

Start date
2018-10-30
Primary completion
2018-12-05
Completion
2018-12-05
First posted
2018-10-30
Last updated
2020-07-07

Locations

1 site across 1 country: Netherlands

Source: ClinicalTrials.gov record NCT03725072. Inclusion in this directory is not an endorsement.