NCT03724266

Effect of Using Nanochitosan Versus Calcium Hydroxide as Disinfectant on Pain and Apical Bone Healing

Effect of Using Nanochitosan Versus Calcium Hydroxide as Intracanal Medications on the Postoperative Pain and Apical Bone Healing

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 20 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Effect of Using Nanochitosan versus Calcium Hydroxide as Intracanal Medications on the Postoperative Pain and Apical Bone Healing

Detailed description

PICO approach P (population): maxillary anterior teeth having necrotic pulp with symptomatic apical periodontitis with evidence of apical radiolucency (minimum size 2 mm x 2 mm). I (intervention):0.2% nanochitosan as intracanal medication. C (control): calcium hydroxide paste intracanal medication. O (outcome): Primary outcome: postoperative pain at time interval 4, 12, 24, 48, 72 hours Secondary outcome: 1. Postoperative pain, swelling, palpation, percussion and mobility at one week, 3, 6, 12 months 2. Number of analgesic tablets used at 4, 12, 24, 48, 72 hours and one week. 3. healing of apical periodontitis using CBCT at 3, 6, 12 months

Conditions

• Postoperative Pain
• Healing

Interventions

Type	Name	Description
DRUG	Chitosan	chitosan will be used as intracanal medication
DRUG	Calcium Hydroxide	intracanal medication

Timeline

• Start date: 2018-10-01
• Primary completion: 2020-05-01
• Completion: 2020-12-01
• First posted: 2018-10-30
• Last updated: 2018-11-01