NCT03723733

Compensatory Brain Mechanisms for Amygdala-associated Cognitive Dysfunction: Potential Role of the Cortical Mirror Neuron System

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 350 (estimated)
• Sponsor: University of Electronic Science and Technology of China · Academic / Other
• Sex: All
• Age: 17 Years – 30 Years
• Healthy volunteers: Accepted

Summary

Identify if the mirror neuron system, or other networks, can compensate for amygdala dysfunction, using behavior and structural/functional MRI.

Detailed description

In the present study, investigators aim to investigate amygdala dysfunction \& potential compensation in individuals with high and low traits (e.g. Autism, Anxiety, Depression traits, Alexithymia), high and low stress or protective factors in the environment (social network, early life stress) and different molecular genetic make-up. On the neural level, functional and structural connectivity as well as task-related BOLD activation will be assessed.

Conditions

• Healthy

Interventions

Type	Name	Description
BEHAVIORAL	screen high and low triat subjects	use a range of questionniares to screen screen high and low triat subjects (eg. Autism, Anxiety, Depression traits and social network size)

Timeline

• Start date: 2016-07-01
• Primary completion: 2019-09-01
• Completion: 2019-12-01
• First posted: 2018-10-29
• Last updated: 2018-10-29

Locations

1 site across 1 country: China