NCT03723109

Airway Management During TCI vs RSI Anesthesia Induction

Airway Management and Safety Aspects During Target Controlled Infusion (TCI) Compared to Rapid Sequence Induction (RSI) of Anesthesia in Non-cardiac Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 70 (actual)
• Sponsor: Umeå University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aims of this observational study is to evaluate and compare feasibility of airway management during standardized TCI and RSI anesthesia induction.

Detailed description

The aims of this study are to evaluate and compare feasibility of airway management and risk for desaturation during standardized target controlled infusion (TCI) and rapid sequence induction (RSI) of anesthesia. A conventional way to induce anesthesia, i.e. manual injection of anesthetics, may be more accurate and predictable compared to dosing regimes based on complex mathematical algorithms used in TCI-systems. In addition, today many different models are presented and there is no consensus which kind of TCI-algorithm should be used universally. Moreover, dosing algorithms are most complex and challenging in underweight and morbid obesity. There are many publications on this field, but no data of feasibility of airway management can be found. Indeed, RSI induction is traditionally blamed to be risky and not recommended as a first choice.

Conditions

• Adverse Effect
• Anesthesia
• Airway Complication of Anesthesia

Interventions

Type	Name	Description
PROCEDURE	Induction of anesthesia	Standardized TCI and RSI anesthesia induction

Timeline

• Start date: 2018-10-29
• Primary completion: 2019-02-22
• Completion: 2019-05-31
• First posted: 2018-10-29
• Last updated: 2019-09-26

Locations

1 site across 1 country: Sweden