Clinical Trials Directory

Trials / Terminated

TerminatedNCT03722485

Negative Pressure Wound Therapy With Instillation of Saline Solution Versus Collagenase Ointment in Full-thickness Wounds

Hydromechanical Cleansing With V.A.C. VERAFLO CLEANSE CHOICE™ Dressing and NPWTi-d vs. Collagenase Ointment in the Management of Full-thickness Wounds

Status
Terminated
Phase
N/A
Study type
Interventional
Enrollment
44 (actual)
Sponsor
KCI USA, Inc · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Evaluation of wound bed surface area containing clean, healthy viable tissue in full-thickness wounds.

Detailed description

This study evaluates changes in wound bed surface area of clean, healthy viable tissue in subjects with full-thickness wounds using negative pressure wound therapy with instillation of saline solution versus a collagenase ointment.

Conditions

Interventions

TypeNameDescription
DEVICENegative Pressure Therapy w/ instillation and dwell (NPWTi-d)Negative Pressure Therapy at -125mmHg for 3.5 hours followed by 10 minute dwell of saline solution for 6-9 days.
BIOLOGICALCollagenase OintmentCollagenase ointment applied daily to the wound and covered with secondary dressing for 6-9 days.

Timeline

Start date
2018-12-12
Primary completion
2022-04-19
Completion
2022-04-19
First posted
2018-10-29
Last updated
2024-10-16
Results posted
2023-06-22

Locations

10 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03722485. Inclusion in this directory is not an endorsement.