NCT03720691

rTMS Treatment in Vascular Parkinsonism

Effect of Repetitive Transcranial Magnetic Stimulation in Vascular Parkinsonism

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (estimated)
• Sponsor: Inje University · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Vascular parkinsonism (VP), parkinsonism resulting from ischemic cerebrovascular disease, was suggested in 1929. The main features are wide-based gait, postural instability, and falls, which make patients with VP frustrated. Currently, the treatment is challenging. Transcranial magnetic stiumation is a noninvasive procedure using electromagnetic induction to stimulate brain, and repetitive transcranial magnetic stiumation (rTMS) can selectively change brain activity to enhance desired effects. The aim of this study is to explore the therapeutic effect of rTMS for the VP.

Conditions

• Vascular Parkinsonism

Interventions

Type	Name	Description
DEVICE	Real rTMS Supplementary motor area	There will be a series of four rTMS blocks separated by 10 minutes. Each block will consist of 15 to 25 pulse trains of 1-second duration at 25 Hz, with an intertrain interval of 10 seconds.
DEVICE	Sham rTMS Supplementary motor area	There will be no real brain stimulation in Sham rTMS, and participant will be blinded.

Timeline

• Start date: 2018-12-01
• Primary completion: 2024-12-01
• Completion: 2025-12-01
• First posted: 2018-10-25
• Last updated: 2018-10-30

Locations

1 site across 1 country: South Korea