NCT03718988

SWAP-MEAT: Study With Appetizing Plant Food - Meat Eating Alternatives Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 38 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study aims to investigate the impact of replacing meat consumption with plant-based meat alternative consumption on cardiovascular health, the gut microbiome, and metabolic status.

Detailed description

Plant-based meat alternatives that closely emulate animal protein provide a new opportunity to decrease meat consumption worldwide. Decreasing meat consumption and shifting to a plant-based diet has been linked to improvements in physical health, including decreased risk of cardiovascular disease, metabolic syndrome, and type 2 diabetes (Kahleova, Levin, \& Barnard, 2017). However, the extent to which plant-based meat alternatives specifically can modulate biomarkers of physical health, particularly TMAO and IGF-1, and the gut microbiome remain relatively unexplored. It is also largely unknown to what extent consumers can feasibly and sustainably exchange meat products for plant-based meat alternatives for extended periods of time. Plant-based meat alternatives offer a promising way to support consumers' shift to a plant-based diet, and in turn, to potentially improve levels of TMAO and IGF-1 and decrease cardiovascular risk. Thus, the investigators hypothesize that consumer levels of TMAO and IGF-1 will be improved after 8 weeks of consuming plant-based meat alternative products, as compared to 8 weeks of consuming traditional meat products.

Conditions

• Microbiome
• Immune Function
• Cardiovascular Diseases

Interventions

Type	Name	Description
BEHAVIORAL	Meat products	Traditional meat products (beef burger patties, pork sausage, etc.)
BEHAVIORAL	Plant Alternative products	Plant-based alternatives (The Beyond Burger, Beyond Sausage, etc.)

Timeline

• Start date: 2019-01-17
• Primary completion: 2019-12-05
• Completion: 2019-12-05
• First posted: 2018-10-25
• Last updated: 2023-02-21

Locations

1 site across 1 country: United States