NCT03717818

Mechanisms of Change in Brief Treatment for Borderline Personality Disorder

Mechanisms of Change in Brief Treatment for Borderline Personality Disorder: A Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: University of Lausanne Hospitals · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

The present two-arm randomized controlled study aims at testing the effects (i.e., symptom reduction) and the underlying mechanisms of change associated with a brief psychiatric treatment (10 sessions over 4 months), compared with treatment as usual. Participants undergo assessments at four points (intake, 2 months, discharge and 12 month follow-up). In addition to symptom measures, all individuals undergo a two-step assessment for the potential mechanisms of change (i.e., emotion and socio-cognitive processing): a) behavioural and b) neurofunctional. We hypothesize that change in the mechanisms explains the treatment effects. The present study uses an innovative treatment of BPD and at the same time a sophisticated assessment procedure to demonstrate the critical role of psychobiological change in emotion and sociocognitive processing in brief treatments. It will help increase the effectiveness of initial treatment phase for BPD and help diminish the societal burden of disease related with BPD. This study is funded by the Swiss National Science Foundation (SNSF).

Conditions

• Borderline Personality Disorder

Interventions

Type	Name	Description
BEHAVIORAL	Good Psychiatric Management - Brief	specific interventions as defined by Gunderson and Links (2014)
BEHAVIORAL	treatment as usual	non-specific intervention

Timeline

• Start date: 2018-10-19
• Primary completion: 2022-12-01
• Completion: 2022-12-01
• First posted: 2018-10-24
• Last updated: 2018-10-25

Locations

1 site across 1 country: Switzerland