NCT03717649

Negative Venous Line Pressure in a Miniaturised Cardiopulmonary Bypass Circuit (CPB)

Negative Venous Line Pressure in a Miniaturised Cardiopulmonary Bypass Circuit - the Influence of a Fenestrated Venous Cannula and Its Effect on Pump Flow

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 48 (actual)
• Sponsor: University Hospital Plymouth NHS Trust · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Study to measure the ability of a 'fenestrated' venous line cannula to reduce the negative line pressure seen with kinetic-assist active venous drainage (KAVD) in a standard miniaturised cardiopulmonary bypass circuit and thereby increase the flow characteristics of the bypass pump.

Detailed description

To investigate whether a new venous drainage pipe (cannula) which has three sets of drainage holes (three-stage) compared with the standard two-stage cannula, or a three-stage which also has additional windows (fenestrations), can improve the drainage of blood into the circuit, reducing the negative pressure produced and increase the blood flow delivered to the patient. Patients who consent to participate will be randomly assigned to one of three types of venous cannula: 1. Standard venous cannulation with a two-stage venous cannula 2. The three-stage cannula (91437C, Medtronic) 3. The fenestrated three-stage cannula (MC2X, Medtronic)

Conditions

• Heart Surgery

Interventions

Type	Name	Description
DEVICE	Conventional 2-stage venous cannula	venous cannula
DEVICE	Conventional 3-stage venous cannula	venous cannula
DEVICE	Fenestrated 3-stage venous cannula	venous cannula

Timeline

• Start date: 2016-01-12
• Primary completion: 2016-10-31
• Completion: 2016-10-31
• First posted: 2018-10-24
• Last updated: 2018-10-24