NCT03716219

The Effect of 10-Week Exercise Training on Children With Asthma

Exercise Training in Children and Adults: Mechanisms of Allaying Inflammation in Asthma

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of California, Irvine · Academic / Other
• Sex: All
• Age: 8 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The goal of this research is to determine whether 10-weeks of exercise training can benefit asthmatic children and young adults with a history of exercise-induced bronchoconstriction (EIB). The investigators will also study an exciting newly discovered aspect of gene expression regulation in the white blood cells known as epigenetics: a process that takes place when genomic changes happen as a result of exposure to the environment. This study is based on emerging exciting new data from this and other laboratories demonstrating that (a) white blood cells play an important role in bronchoconstriction in children, (b) gene and cytokine expression in circulating white blood cells are abnormal in asthma and (c) brief exercise may change genomic and inflammatory- profiles of these cells.Physical activity is an essential component of growth and health in children, thus, this research will lead to improved clinical uses of exercise as preventive and adjunctive therapy in the current epidemic of childhood asthma

Conditions

• Asthma in Children

Interventions

Type	Name	Description
OTHER	Exercise Training	Physical activity in children and adults with asthma.

Timeline

• Start date: 2013-10-10
• Primary completion: 2013-10-10
• Completion: 2013-10-10
• First posted: 2018-10-23
• Last updated: 2021-02-12

Locations

1 site across 1 country: United States