Clinical Trials Directory

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UnknownNCT03715296

Lenalidomide Based Immunotherapy in the Treatment of DLBCL

Lenalidomide Based Immunotherapy Efficacy Related Molecular Biomarker in Diffuse Large B-cell Lymphoma

Status
Unknown
Phase
Study type
Observational
Enrollment
200 (estimated)
Sponsor
Ruijin Hospital · Academic / Other
Sex
All
Age
16 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This study is to evaluate the efficacy related molecular biomarker of Lenalidomide plus RCHOP or RICE in the treatment of de novo or Refractory and Relapsed DLBCL patients

Conditions

Interventions

TypeNameDescription
DRUGLenalidomide 25mgLenalidomide 25mg/d PO d1-10 Plus Rituximab 375 mg/m2 IV d1, Cyclophosphamide 750mg/m2 IV d2, Doxorubicin 50mg/m2 IV d2, Vincristine 1.4 mg/m2 IV d2, Prednisone 60 mg/m2 PO d2-6 OR Ifosfamide 1500mg/m2/d iv d1-3, Carboplatin 5\*\[GFR(ml/min)+25\]mg/d iv d2, Etoposide 100mg/m2/d iv d1-3,

Timeline

Start date
2018-10-18
Primary completion
2020-09-15
Completion
2020-09-15
First posted
2018-10-23
Last updated
2019-07-08

Locations

1 site across 1 country: China

Regulatory

Source: ClinicalTrials.gov record NCT03715296. Inclusion in this directory is not an endorsement.