Trials / Terminated
TerminatedNCT03714854
Study of Motor Control Mechanisms in DBS-implanted Parkinson's Disease Patients
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 6 (actual)
- Sponsor
- University Hospital, Grenoble · Academic / Other
- Sex
- All
- Age
- 30 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Akinesia is one of the most prominent symptom in Parkinson's Disease (PD) patients. It typically consists in a inability to initiate voluntary movement, and it affects patients' quality of life. This study aims at exploring the influence of Deep Brain Stimulation (DBS) in the quality of motor control, and particularly of voluntary movement initiation, and its neural correlates. They will be evaluated using behavioral and motor tasks together with Transcranial Magnetic Stimulation (TMS) and electrophysiology (EMG and EEG).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | transcranial magnetic stimulation | TMS will be delivered on the sensory-motor system and the inhibitory motor control network while patients are performing behavioral and motor tasks. Brain and muscle activity will be recorded concurrently using EEG and EMG respectively. |
Timeline
- Start date
- 2018-12-05
- Primary completion
- 2021-02-12
- Completion
- 2021-02-12
- First posted
- 2018-10-22
- Last updated
- 2023-01-10
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT03714854. Inclusion in this directory is not an endorsement.