Clinical Trials Directory

Trials / Completed

CompletedNCT03714646

Beta Glucan and Acetate Production

The Effects of Beta Glucan on Acetate Production and Human Substrate Metabolism

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
24 (actual)
Sponsor
Maastricht University Medical Center · Academic / Other
Sex
Male
Age
30 Years – 65 Years
Healthy volunteers
Accepted

Summary

Based on our hypothesis that orally administered resistant starch and beta glucan will be fermented into a SCFA pattern high in acetate and that this will lead to beneficial effects on human substrate and energy metabolism, we aim to address the following primary objective: To investigate the effects of an acute administration of inulin/beta glucan in combination with resistant starch on fecal and plasma acetate, as well as on fasting and postprandial substrate and energy metabolism in lean normoglycemic men and obese, prediabetic men.

Conditions

Interventions

TypeNameDescription
DIETARY_SUPPLEMENTbeta glucan and resistant starch12g per day the day before the CID Resistant starch 7.5 g
DIETARY_SUPPLEMENTPlaceboisocaloric maltodextrin before the CID
DIETARY_SUPPLEMENTbeta gluten12 g beta gluten there day before the CID

Timeline

Start date
2018-09-05
Primary completion
2019-05-10
Completion
2019-05-10
First posted
2018-10-22
Last updated
2020-01-13

Locations

1 site across 1 country: Netherlands

Source: ClinicalTrials.gov record NCT03714646. Inclusion in this directory is not an endorsement.