NCT03712683

Thyroxin in Subclinical Hypothyroidism

Prevalence of Subclinical Hypothyroidism in Women With Unexplained Infertility and the Effect of Thyroxin on Pregnancy Rate

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 168 (actual)
• Sponsor: Hawler Medical University · Academic / Other
• Sex: Female
• Age: 18 Years – 42 Years
• Healthy volunteers: Not accepted

Summary

Subclinical hypothyroidism(SCH) is the elevated thyroid stimulating hormone (TSH) with normal free Thyroxine levels and it is a mild or compensated form of primary hypothyroidism. It has been suggested that SCH is more prevalent in infertile women (especially in women with ovulatory disorders.Various rates of SCH was reported in infertile women in different populations

Detailed description

Despite well-established recommendations on screening and treatment of overt hypothyroid in infertile women, there is a controversy regard the treatment of SCH in infertile women . There are few published data on the prevalence of SCH and the outcome of treatment of SCH in infertile women, many were conducted during IVF cycles . Moreover there are inconsistent results in these studies being authors advised to treat SCH before IVF and some other articles find out no any benefit regarding treatment with Thyroxine in SCH

Conditions

• Sub Clinical Hypothyroidism
• Pregnancy Loss

Interventions

Type	Name	Description
DRUG	Thyroxine	Thyroxine was prescribed with the diagnosis of SCH and continued when pregnancy was confirmed

Timeline

• Start date: 2016-09-01
• Primary completion: 2017-07-01
• Completion: 2017-07-01
• First posted: 2018-10-19
• Last updated: 2018-10-29