NCT03707652

Open-label Study to Assess Increasing Levels of NAD+(Nicotinamide Adenine Dinucleotide)

Three-Day Dosing NAD + Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 8 (actual)
• Sponsor: Supplement Formulators, Inc. · Industry
• Sex: All
• Age: 30 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to assess an effective single oral supplement or combination of oral supplements for increasing whole blood NAD+ levels.

Detailed description

This is a open-label dose finding study to detect an effective single oral supplement or combination of oral supplements for enhancing whole blood levels of NAD+. Each subject will receive a specific dose of the formulation once daily for 3 days followed by a washout period. Upon completion of the treatment phase, there is a post-treatment period of assessments. Participants receive assessments of blood tests, vital signs, body weight with completion of questionnaires. The primary objective of the study is to identify the ideal dosage of an oral supplement to increase whole blood NAD+ levels in adults. The secondary objective of the study is to monitor for safety from a change in fasting blood chemistry panel parameters after three day's dosing compared to cycle baseline.

Conditions

• Increase in Blood Levels of Nicotinamide Adenine Dinucleotide (NAD+)

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Oral supplement A	1, 2 or 4 capsules daily of oral supplement A for 3 days
DIETARY_SUPPLEMENT	Oral supplement B	4 capsules daily of oral supplement B for 3 days
DIETARY_SUPPLEMENT	Oral supplement C	1,2 or 4 capsules daily of oral supplement C for 3 days
DIETARY_SUPPLEMENT	Oral supplement D	1 or 2 tablets daily of oral supplement D for 3 days
DIETARY_SUPPLEMENT	Oral Supplement D in combination with oral supplement C	1 or 2 tablets of oral supplement D in combination with 2 or 4 capsules of oral supplement C for 3 days

Timeline

• Start date: 2018-03-12
• Primary completion: 2018-05-16
• Completion: 2018-05-24
• First posted: 2018-10-16
• Last updated: 2018-10-18

Locations

1 site across 1 country: United States