NCT03706027

Study Comparing Two Different Schedules of Radiation for Early-stage Lung Cancer

Three- Versus Five-Fraction Regimens of Stereotactic Body Radiotherapy for Peripheral Early-Stage Non-Small-Cell Lung Cancer: A Prospective Randomized Phase II Study

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University of Rochester · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study's goal is to find out if the kind of side effects people experience from radiation is different depending on the schedule of their radiation treatment. Patients will be randomly assigned to either the 3 Fraction or 5 Fraction schedule of radiation. After patients complete radiation treatment, they will follow up with their radiation oncologist.

Conditions

• Lung Cancer

Interventions

Type	Name	Description
DEVICE	radiation therapy-3 fractions	Radiation therapy given in a 3 fraction schedule (over 3 days). Total dose is 54 Grays.
DEVICE	Radiation therapy-5 fractions	Radiation therapy given in 5 fractions (over 5 days). Total dose is 60 Grays.

Timeline

• Start date: 2018-12-15
• Primary completion: 2025-11-15
• Completion: 2026-11-15
• First posted: 2018-10-15
• Last updated: 2025-04-24

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study