Trials / Terminated
TerminatedNCT03705923
Effect of Bariatric Surgery on Brain Insulin Sensitivity
Metabolic Characterization of Subjects With Adipositas Before and After Bariatric Surgery
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 3 (actual)
- Sponsor
- University Hospital Tuebingen · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
Adiposity is associated with prediabetes and type 2 diabetes. In very severe cases of adiposity in combination with type 2 diabetes, bariatric surgery has proven to be a successful therapy option. So far the molecular mechanisms that lead to an improvement of type 2 diabetes after bariatric surgery are not fully understood. It is planned to characterize the metabolic and neuroendocrine changes in subjects before and after bariatric surgery. One special focus of the study is brain insulin resistance, a condition known to be associated with obesity with impact on the brain and whole body metabolism.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Bariatric surgery | laparoscopic Roux-en-Y gastric bypass or laparoscopic sleeve gastrectomy |
Timeline
- Start date
- 2018-12-01
- Primary completion
- 2020-12-01
- Completion
- 2020-12-01
- First posted
- 2018-10-15
- Last updated
- 2022-01-05
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT03705923. Inclusion in this directory is not an endorsement.