NCT03701529

Effect of Anesthetic Agents on Optic Nerve Sheath Diameter

Effect of Anesthetic Agents (Propofol, Sevoflurane) on Optic Nerve Sheath Diameter(ONSD) in Patients Undergoing Robot-assisted Laparoscopic Gynecology Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (actual)
• Sponsor: Hallym University Kangnam Sacred Heart Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The present study is to evaluate the effect of anesthetic agents ( propofol , sevoflurane) on intracranial pressure of female patients undergoing laparoscopic-robotic surgery.

Detailed description

Anesthetic agents (propofol and sevoflurane)have different effect on intracranial pressure. Sevoflurane when used over 0.5 minimum alveolar concentration, dilates intracranial vasculature and increases intracranial pressure. On the other hand, propofol decreases intracranial blood pressure and intracranial pressure is maintained or decreases. Optic nerve sheath diameter is a feasible diagnostic tool in evaluating intracranial pressure. Female patients undergoing robot-assisted laparoscopic hysterectomy or myomectomy are evaluated.

Conditions

• Uterus Myoma
• Uterine Cancer

Interventions

Type	Name	Description
DRUG	Sevoflurane	1.5-2.5 vol % sevoflurane is used for maintenance of anesthesia.
DRUG	Propofol	2-5 mcg/ml of propofol is used for maintenance of anesthesia.

Timeline

• Start date: 2018-10-15
• Primary completion: 2019-09-16
• Completion: 2019-09-16
• First posted: 2018-10-10
• Last updated: 2020-09-04

Locations

1 site across 1 country: South Korea