NCT03698175

Effects of a Brief Mental Exercise on Emotional Processing

Can Brief Daily Mental Exercises Change the Way the Human Brain Processes Certain Kinds of Information?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: University of Oxford · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to explore whether a brief mental exercise (developed and widely advocated in the field of positive psychology) can change the processing of emotion-related information in a similar way as previously observed for antidepressant drugs. Healthy volunteers are randomly allocated to a 7-day practice of the "Three Good Things" (TGT) exercise or a previously used placebo exercise (unspecified childhood memory recall) with study participants as well as investigators being blind as to which practice is conducted. After a 7-day practice period, all study participants undergo testing with the Oxford Emotional Test Battery, an established battery of cognitive tasks that allow to assess how emotional information is processed. The working hypothesis of the study is that the TGT exercise, as compared to the placebo exercise, can push the processing of emotional information towards a prioritisation of positive (relative to negative) input.

Detailed description

Background and objective: Previous research indicates that various physiological treatments for depression (especially antidepressant drugs) can induce positive biases in emotional information processing and it has been suggested that this might be a crucial common mechanism through which they exert their clinical effects. This study aims to investigate whether similar positive biases can also be induced by a brief mental exercise (developed and widely used within the field of positive psychology) that has previously been shown to have antidepressant and/or happiness-enhancing effects. Methods: Using a double-blind, parallel-group design, 100 healthy volunteers (male and female) are randomly allocated to a 7-day mental exercise practice conducting either the widely reported Three Good Things (TGT) exercise or a previously established placebo condition (unspecific childhood memory recall). After 7 days of practice, all participants undergo testing with the Oxford Emotional Test Battery in order to assess emotional information processing in different cognitive domains. This battery consists of a facial expression recognition task, an emotional categorization task, an emotional dot probe task, an emotional recall task and an emotional recognition task. In addition, prior to and immediately after the 7-day practice period salivary cortisol awakening response and subjective state (using various questionnaires) is assessed. Hypotheses: The working hypothesis of the study is that, similar to physiological antidepressant interventions, the TGT exercise (as compared to the placebo exercise) might induce biases towards positive stimuli in multiple cognitive domains. Implications of the study: This study will show whether engaging in a simple mental exercise can alter emotional information processing in a similar way as previously observed for antidepressant drugs and other physiological interventions.

Conditions

• Emotional Processing
• Mental Exercise

Interventions

Type	Name	Description
BEHAVIORAL	Three good things exercise	Participants are asked to remember each evening three things that went well during their day and to write them down in a journal including a short explanation of why they think each of them has happened.
BEHAVIORAL	Placebo exercise	Participants are asked to briefly recall a childhood memory (no further specification) and to write it down including a short explanation why they think it has happened.

Timeline

• Start date: 2017-05-24
• Primary completion: 2018-10-10
• Completion: 2018-10-10
• First posted: 2018-10-05
• Last updated: 2019-04-18

Locations

1 site across 1 country: United Kingdom