NCT03695432

Probiotic and Influenza Vaccination to Reducing Influenza-like Illness Incident in Elderly

Role of Probiotic and Influenza Vaccination on Immune Response Enchancement and Influenza-Like Illness Incidence Reduction in Elderly

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 910 (actual)
• Sponsor: Indonesia University · Academic / Other
• Sex: All
• Age: 60 Years – 90 Years
• Healthy volunteers: Accepted

Summary

To asses the effect of the probiotic and influenza vaccination alone and combination on enhancing immune response to influenza-like illness (ILI) and reducing ILI incidence in the elderly

Detailed description

To see percetange of subjects seroconvertion and seroprotection before and after intervention in the elderly (\>60 years), and monitored for 6 months.

Conditions

• Influenza-like Illness

Interventions

Type	Name	Description
BIOLOGICAL	Flubio	Flubio (A/California/7/2009, A/Texas/50/2012 and B/Massachusetts/2/2012) Vaccine 0,5 ml for every subjects The vaccine will be given intramuscularly
DIETARY_SUPPLEMENT	Lacidofil	Lacidofil (Lactobacillus acidophilus Rossel-52 and Lactobacillus rhamnosus Rosell-11 with maltodextrin 211 mg, magnesium stearat 8 mg and ascorbic acid 1 mg) antibiotic The antibiotic will be given 2 times each day for 6 months
OTHER	Placebo Vaccine	Nacl 0,9% 0,5 ml The placebo vaccine will be given intramuscularly
OTHER	Placebo probiotic	Capsul

Timeline

• Start date: 2014-10-01
• Primary completion: 2015-04-01
• Completion: 2016-07-01
• First posted: 2018-10-04
• Last updated: 2018-10-05

Locations

1 site across 1 country: Indonesia