NCT03688243

Non Exudative AMD Imaged With SS-OCT

Non Exudative Age-Related Macular Degeneration Imaged With Swept Source Optical Coherence Tomography

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 225 (actual)
• Sponsor: Boston Image Reading Center · Industry
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

The investigators wish to better understand the role of the choriocapillaris (CC) in the formation and progression of non-exudative in age related macular degeneration (armd) by imaging the retinal pigment epithelium (rpe) and the choroidal microvasculature and by studying their inter-dependence to determine if the loss of the CC could prove useful as an anatomic clinical trial endpoint in future drug trials.

Detailed description

This is a longitudinal observational study where the investigators will look at 450 subjects, 200 with intermediate AMD in at least one eye, or with AMD in one eye, either early or intermediate, and with late AMD (exudative) in the other eye, and 250 subjects with nGA or GA in at least one eye.

Conditions

• Dry Macular Degeneration

Interventions

Type	Name	Description
DEVICE	SS-OCT imaging	All subjects will undergo retinal imaging using the Zeiss PlexElite SS-OCT, a non-contact, non-invasive ocular imaging instrument

Timeline

• Start date: 2018-01-18
• Primary completion: 2023-03-01
• Completion: 2023-03-01
• First posted: 2018-09-28
• Last updated: 2022-03-10

Locations

5 sites across 2 countries: United States, Australia

Regulatory

• FDA-regulated device study