Trials / Completed
CompletedNCT03687567
A Retrospective Study on the Effect of HBA or HBB Genetic Defects on Early Embryonic Development
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 737 (actual)
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
Thalassemia is an anemia or pathological state caused by compounding absently or inadequately of one or more globin chains of hemoglobin due to the defects of the globin gene,and the carrying rate is high in southern China. Although there are many studies of Thalassemia, the relationship between the globin gene defects and the early embryo development has not been reported. This study intends to carry out a retrospective analysis on the embryonic development of the patients with thalassemia assisted by PGD from January 1, 2011 to now in our hospital, to explore whether the HBA or HBB gene defects have a certain influence on the early embryo development, so as to accumulate certain data for reproductive health research.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Preimplantation genetic diagnosis |
Timeline
- Start date
- 2013-09-01
- Primary completion
- 2018-07-31
- Completion
- 2020-12-31
- First posted
- 2018-09-27
- Last updated
- 2022-01-11
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT03687567. Inclusion in this directory is not an endorsement.