Clinical Trials Directory

Trials / Completed

CompletedNCT03687515

Efficacy and Safety of Budesonide Inhalation Suspension for the Treatment of Chronic Rhinosinusitis With Polyposis.

Efficacy and Safety of Budesonide Inhalation Suspension Via Transnasal Nebulization Compared With Budesonide Aqueous Nasal Spray and Oral Steroids for the Treatment of Chronic Rhinosinusitis With Polyposis.

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
91 (actual)
Sponsor
Beijing Tongren Hospital · Academic / Other
Sex
All
Age
23 Years – 64 Years
Healthy volunteers
Not accepted

Summary

Topical and systemic steroids constitute the first choice in medical treatment for nasal polyps. This study aimed to evaluate the efficacy and safety of a short course of budesonide inhalation suspension via transnasal nebulization in the preoperative management of chronic rhinosinusitis with nasal polyposis. The second aim was to compare budesonide inhalation suspension with budesonide aqueous nasal spray and oral prednisone in nasal polyp treatment.

Conditions

Interventions

TypeNameDescription
DRUGbudesonide1mg/2ml Pulmicort Respules BIS twice daily
DRUGbudesonidenasal spray 256μg BID
DRUGPrednisoneoral prednisone 24mg QD

Timeline

Start date
2015-01-01
Primary completion
2016-12-03
Completion
2017-11-30
First posted
2018-09-27
Last updated
2018-09-27

Source: ClinicalTrials.gov record NCT03687515. Inclusion in this directory is not an endorsement.