Clinical Trials Directory

Trials / Completed

CompletedNCT03687255

Safety and Efficacy Study of Cefepime-AAI101 in the Treatment of Complicated Urinary Tract Infections

A Phase 3, Randomized, Double-Blind, Study to Evaluate the Efficacy and Safety of Cefepime-AAI101 Compared to Piperacillin/Tazobactam in the Treatment of Complicated Urinary Tract Infections, Including Acute Pyelonephritis.

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
1,043 (actual)
Sponsor
Allecra · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Multi-center, randomized, double-blind, non-inferiority study of cefepime 2 g/AAI101 500 mg combination compared to piperacillin 4 g/tazobactam 500 mg in a population of adult patients with cUTI or AP. The study will be conducted in approximately 115 sites located in the EU, the US, Central, South America and South Africa.

Conditions

Interventions

TypeNameDescription
DRUGcefepime/AAI101 combinationcefepime 2 g / AAI101 500 mg
DRUGPiperacillin/tazobactampiperacillin 4 GM / tazobactam 500 MG

Timeline

Start date
2018-09-24
Primary completion
2020-01-30
Completion
2020-02-15
First posted
2018-09-27
Last updated
2020-03-10

Locations

24 sites across 19 countries: United States, Argentina, Belarus, Bulgaria, Croatia, Estonia, Georgia, Hungary, Latvia, Lithuania, Mexico, Peru, Poland, Russia, Serbia, Slovakia, South Africa, Spain, Ukraine

Regulatory

Source: ClinicalTrials.gov record NCT03687255. Inclusion in this directory is not an endorsement.