NCT03686982

The Impact of Supplementation With Novel Prototype Nutrition Bar on Nitric Oxide Bioavailability and Measures of Athlete Performance

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: PepsiCo Global R&D · Industry
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Dietary nitrate, L-citrulline, epicatechin, vitamin C and glutathione have the potential to improve nitric oxide (NO) bioavailability, in humans, by influencing both the nitrate-nitrite-NO and NO synthase-dependent pathways, and the storage of NO. The study is designed to assess the efficacy of a newly developed product containing a mixture of these compounds. Specifically, the study will assess if the product is capable of increasing NO bioavailability and if this results in positive effects on exercise economy and intermittent exercise performance. These outcome measures have been chosen because they have previously been positively impacted by an increase in NO bioavailability.

Conditions

• Exercise Performance

Interventions

Type	Name	Description
OTHER	Active Nitrate Bar	Bar containing Nitrate, L-citrulline; epicatechin; vitamin C and glutathione
OTHER	Placebo Bar	No active ingredients

Timeline

• Start date: 2017-05-01
• Primary completion: 2018-04-15
• Completion: 2018-04-30
• First posted: 2018-09-27
• Last updated: 2018-09-27

Locations

1 site across 1 country: United Kingdom