Clinical Trials Directory

Trials / Completed

CompletedNCT03685539

DECT in Imaging Patients With Solid Organ Cancer With Intracranial Metastasis

Advanced CT Imaging Optimization for the Detection of Intracranial Metastasis

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
42 (actual)
Sponsor
M.D. Anderson Cancer Center · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This trial studies how well dual energy computed tomography (DECT) works in imaging patients with solid organ cancer that has spread to the brain. Imaging techniques, such as DECT, may help find and diagnose tumor cells and find out how far the tumor cells have spread in the brain.

Detailed description

PRIMARY OBJECTIVES: I. To optimize two major parameters of computed tomography (CT) imaging for optimal detection of intracranial metastatic lesions. Ia. Virtual monochromatic image reconstruction. Ib. Contrast bolus timing. II. To measure the detection accuracy of CT compared to the diagnostic standard of care gadolinium-based "Gamma Knife (GK)" protocol magnetic resonance imaging (MRI). OUTLINE: Within 7 days before the standard Gamma Knife MRI, patients undergo DECT scan over 6 seconds at 1.5, 5, 10, and 20 minutes after receiving the contrast agent.

Conditions

Interventions

TypeNameDescription
PROCEDUREDual-Energy Computed TomographyUndergo DECT

Timeline

Start date
2018-08-24
Primary completion
2023-08-29
Completion
2023-08-29
First posted
2018-09-26
Last updated
2023-08-31

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT03685539. Inclusion in this directory is not an endorsement.