Trials / Completed
CompletedNCT03685305
Weight Loss and Cognitive Function in Adults
Weight Loss and Cognitive Function in Middle-Aged and Older Adults
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 33 (actual)
- Sponsor
- Virginia Polytechnic Institute and State University · Academic / Other
- Sex
- All
- Age
- 50 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
More than two-thirds of middle-aged and older adults are overweight, which places them at greater risk of disability and higher medical expenses. Lifestyle interventions which promote weight loss for this population are needed. However, it is not known how different weight loss approaches impact brain (cognitive) functions, such as memory and attention. The investigator's investigation aims to improve adherence to a hypocaloric diet prescription through improved attention and inhibitory control, reduced hunger, and increased satiety. The objectives of this pilot study are to: 1) determine the feasibility and establish proof-of-concept; 2) establish proficiency and feasibility of the proposed cognitive function assessments; and 3) obtain preliminary data for effect size generation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Hypocaloric diet with hunger reduction strategy | Participants will be counseled to consume a hypocaloric diet during the 4-week weight loss phase. Counseling will include specific instructions on a dietary manipulation which may reduce hunger, in order to facilitate dietary adherence.This will include tracking of the strategy. They will also be provided a pedometer and instructed to attain 10,000 steps per day. |
| BEHAVIORAL | Hypocaloric diet without hunger reduction strategy | Participants will be counseled to consume a hypocaloric diet during the 4-week weight loss phase. They will also be provided a pedometer and instructed to attain 10,000 steps per day. |
Timeline
- Start date
- 2018-08-06
- Primary completion
- 2019-08-14
- Completion
- 2020-03-31
- First posted
- 2018-09-26
- Last updated
- 2025-03-21
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03685305. Inclusion in this directory is not an endorsement.