NCT03684876

Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery

Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery: a Prospective Observational Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 40 (estimated)
• Sponsor: Centre Hospitalier Universitaire, Amiens · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Following cardiac surgery, right ventricular function may be altered leading to increase central venous pressure and decrease in renal blood flow. The investigator's standard care includes use of diuretic to avoid interstitial fluid accumulation. The aim of the study is to assess cardiac and renal function before and after depletion by using diuretics

Detailed description

The study will compare cardiac and renal data before and 6 hours after use of diuretic * Echocardiographic measure of right function (S wave, TAPSE, ventricle surfaces, inferior vena cava diameter) and left function (LVEF, cardiac output * Renal function: cumulative diuresis, creatinine level variation and incidence of acute kidney injury using KDIGO classification (creatinine level\>26.5 or diuresis\<0.05 ml kg-1 h-1)

Conditions

• Cardiorenal Syndrome

Interventions

Type	Name	Description
PROCEDURE	diuretic use	use of diuretic

Timeline

• Start date: 2018-06-01
• Primary completion: 2024-06-01
• Completion: 2024-06-01
• First posted: 2018-09-26
• Last updated: 2023-05-17

Locations

1 site across 1 country: France