Trials / Active Not Recruiting
Active Not RecruitingNCT03684447
Neural and Antidepressant Effects of Propofol
- Status
- Active Not Recruiting
- Phase
- Phase 2 / Phase 3
- Study type
- Interventional
- Enrollment
- 48 (estimated)
- Sponsor
- University of Utah · Academic / Other
- Sex
- All
- Age
- 18 Years – 55 Years
- Healthy volunteers
- Not accepted
Summary
This study will compare the antidepressant effects of propofol at two different doses while measuring potential treatment-related biomarkers.
Detailed description
Aim 1: Compare the clinical antidepressant effects of high-dose versus low-dose propofol. Aim 2: Characterize the dose-dependent effects of propofol on brain function and gene expression
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Propofol | Series of 6 treatments with propofol. |
| DRUG | Propofol | Series of 6 treatments with propofol. May be able to cross over and receive 6 additional treatments with the high dose of propofol. |
Timeline
- Start date
- 2019-04-21
- Primary completion
- 2022-12-31
- Completion
- 2024-07-01
- First posted
- 2018-09-25
- Last updated
- 2024-05-07
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03684447. Inclusion in this directory is not an endorsement.