NCT03680911

NAC for Head Trauma-induced Anosmia

Early N-Acetyl Cysteine Treatment for Head Trauma-induced Anosmia

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 7 (actual)
• Sponsor: University of Miami · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study will compare administration of N-Acetyl Cysteine (NAC) versus placebo for the treatment of olfactory loss due to head injury. The hypothesis is that treatment with NAC acutely after head injury will result in improved olfactory function

Conditions

• Anosmia
• Head Trauma

Interventions

Type	Name	Description
DRUG	N Acetyl Cysteine	2 g PO BID for 4 days, then 1.5 g PO BID for 2 days
DRUG	Placebo oral capsule	2 g PO BID for 4 days, then 1.5 g PO BID for 2 days

Timeline

• Start date: 2018-10-12
• Primary completion: 2020-01-07
• Completion: 2020-01-07
• First posted: 2018-09-21
• Last updated: 2021-02-04
• Results posted: 2021-02-04

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study