NCT03679481

The Effect of Tranexamic Acid on Blood Loss and Transfusion Requirements Following Open Femur Fracture Surgery

• Status: Withdrawn
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: The University of Texas Health Science Center, Houston · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the effect of tranexamic acid (TXA) on blood loss and transfusion requirements in patients with femur fractures requiring open surgical approaches.

Conditions

• Blood Loss Following Open Femur Fracture Surgery

Interventions

Type	Name	Description
DRUG	Tranexamic acid (TXA)	Following induction of anesthesia and prior to surgical incision, patients will receive 1 gram of intravenous TXA mixed in 100cc of normal saline.
DRUG	Normal saline	Following induction of anesthesia and prior to surgical incision, patients will receive 100cc of normal saline.

Timeline

• Start date: 2020-04-01
• Primary completion: 2021-04-01
• Completion: 2021-04-01
• First posted: 2018-09-20
• Last updated: 2019-10-17

Regulatory

• FDA-regulated drug study