Clinical Trials Directory

Trials / Completed

CompletedNCT03678584

Supplementing Intracytoplasmic Sperm Injection Handling Medium With Chaetoglobosin A ( ICSI-CA)

Chaetoglobosin A Supplementation to ICSI Handling Medium

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
300 (actual)
Sponsor
Ibn Sina Hospital · Other Government
Sex
Female
Age
18 Years – 42 Years
Healthy volunteers
Not accepted

Summary

Vienna Consensus has identified 10% damage rate after ICSI as a competency value. Despite the highest quality embryologists doing ICSI, degeneration sometimes occurs due to oocyte factors such as the fragile membrane, etc. Chaetoglobosin A serves to facilitate spindle or pronuclear transfer procedures helping to reduce the damage rate with no harm reported. Using Chaetoglobosin A during ICSI could serve to rescue some oocytes from the degeneration allowing for more chances of viable zygotes.

Conditions

Interventions

TypeNameDescription
OTHERMedium Supplemented with Chaetoglobosin AA medium with in-house supplementation of Chaetoglobosin A to decrease oocyte degeneration after ICSI and improve the survival rate

Timeline

Start date
2018-09-25
Primary completion
2019-05-02
Completion
2019-05-03
First posted
2018-09-19
Last updated
2019-05-07

Locations

3 sites across 1 country: Egypt

Source: ClinicalTrials.gov record NCT03678584. Inclusion in this directory is not an endorsement.