Clinical Trials Directory

Trials / Recruiting

RecruitingNCT03676868

Biology of Cerebral Arteriovenous Malformations and Prognosis of Cerebral Arteriovenous Malformations

Biology of Cerebral Arteriovenous Malformations : Study of the Link Between Blood Biomarkers and the Haemorrhagic Prognosis of Cerebral Arteriovenous Malformations

Status
Recruiting
Phase
Study type
Observational
Enrollment
300 (estimated)
Sponsor
Fondation Ophtalmologique Adolphe de Rothschild · Network
Sex
All
Age
0 Years
Healthy volunteers

Summary

The cerebral arteriovenous malformations correspond to the formation of an entanglement of morphologically abnormal vessels called nidus, which shunt the blood circulation directly from the arterial circulation to the venous circulation. The cerebral arteriovenous malformations are an important cause of hemorrhagic stroke. The hypothesis is that cerebral haemorrhage associated with a cerebral arteriovenous malformations would come from peri-nidal micro-vessels, in connection with infiltration of leucocytes and / or defective maintenance of microvascular integrity by platelets.

Conditions

Timeline

Start date
2018-11-20
Primary completion
2028-11-19
Completion
2028-11-19
First posted
2018-09-19
Last updated
2025-06-25

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT03676868. Inclusion in this directory is not an endorsement.