NCT03675425

The Effects of Phototherapy in Preterm Infants Pda

Chest Shielding for Prevention of a Patent Ductus Arteriosus in Preterm Infants Receiving Phototherapy Effect of Phototherapy

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 54 (estimated)
• Sponsor: Zekai Tahir Burak Women's Health Research and Education Hospital · Academic / Other
• Sex: All
• Age: 3 Days – 1 Week
• Healthy volunteers: Not accepted

Summary

The study was designed to assess whether chest shielding during phototherapy reduces the incidence of PDA, as assessed by serial echocardiographic examinations, in a population of extremely preterm infants born at lower 30 week gestation.

Detailed description

Phototherapy is a therapeutic intervention frequently used for management of neonatal hyperbilirubinaemia in extremely premature infants, especially in the first week when patency of the ductus is a clinical problem. Phototherapy has also been implicated in increased ductal patency. One randomized, controlled trial showed that chest shielding during phototherapy reduced the incidence and severity of PDA by 50% in preterm infants. These findings were mainly based on clinical evaluation of the ductus with echocardiographic studies performed only on a subgroup of infants noted to have a murmur on clinical examination.

Conditions

• Patent Ductus Arteriosus After Premature Birth
• Hyper Bilirubinemia

Interventions

Type	Name	Description
OTHER	Group 1: non chest shielding	non chest childin: infants will be randomized into two different phototherapy groups eco with pad diameter will be measured in before and after phototherapy,
OTHER	Group 2: chest shielding	chest childing: infants will be randomized into two different phototherapy groups eco with pad diameter will be measured in before and after phototherapy,

Timeline

• Start date: 2018-07-08
• Primary completion: 2019-01-30
• Completion: 2019-02-28
• First posted: 2018-09-18
• Last updated: 2018-12-11

Locations

1 site across 1 country: Turkey (Türkiye)